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FAST FORWARD, LLC AND AMPLIMMUNE, INC. JOIN FORCES TO SPEED NEW TREATMENTS TO PEOPLE WITH MS
Amplimmune, Inc., a Maryland-based biotechnology company, and Fast Forward, LLC,
the National Multiple Sclerosis Society's subsidiary devoted to bridging the gap between
research and drug development, today announced a collaboration to support the
development of Amplimmune's AMP-110 therapeutic candidate. This novel and
proprietary biological molecule, or biologic, is specifically designed to target and prevent
the abnormal immune responses associated with multiple sclerosis and other
autoimmune diseases.
The agreement with Amplimmune is the third in a series of growing partnerships
between Fast Forward and emerging biotechnology companies. "We are pleased to
partner with Amplimmune to advance the development of new treatments for MS," said
Dr. Timothy Coetzee, President of Fast Forward. "AMP-110 represents an important
inventive approach to inhibiting inflammatory responses in multiple sclerosis." Adds Dr.
Coetzee, "Modulating the immune system by using costimulatory and coinhibitory
biologics is an active area of research and has significant potential in developing new
therapies for MS. AMP-110 fits our profile for supporting innovative and promising new
treatments for MS."
"Fast Forward's support provides a strong, independent and scientific validation for
developing Amplimmune's AMP-110 for treating MS," said Mr. Michael Richman,
President and CEO of Amplimmune. "Building on the exciting discovery of one of
Amplimmune's founders, Dr. Lieping Chen, at The Johns Hopkins University, we are
pleased to form this collaboration with Fast Forward which will help accelerate AMP-
110 into clinical testing."
The National Multiple Sclerosis Society funds research in a range of scientific areas
including immune mechanisms, genetics, nerve regeneration and symptom
managements. The agreement with Amplimmune is a part of the Society's Fast Forward
initiative through which Fast Forward will partner with young innovative biotechnology
and pharmaceutical companies to develop treatments, diagnostics, medical devices,
and related technologies to treat, reverse and ultimately cure MS. Under the terms of
the agreement, Fast Forward will provide Amplimmune with funds to support preclinical
development of AMP-110. In consideration, Fast Forward will receive warrants to
purchase shares of the company.
Fast Forward's partnership with Amplimmune continues to expand its role in spurring
MS drug development in the emerging biotech market and follows on its successful
alliances with Apitope Internationa l to fund a proof of principle clinical trial for a peptide
therapeutic vaccine and with Provid Pharmaceuticals to develop a novel compound
intended to redirect abnormal immune response. It also builds on Fast Forward's $19
million collaborative partnership with EMD Serono to accelerate innovation and
commercial development of MS therapies through a group of soon to be determined,
mutually agreed upon seed-to-early stage projects. Emerging biotechnology companies
face many challenges in the current economy, and Fast Forward is determined to
deploy its resources to spearhead the continued development of promising MS
therapies
About the National Multiple Sclerosis Society
MS is a chronic, unpredictable neurological disease that affects the central nervous
system. It is thought to be an autoimmune disorder, meaning the immune system
incorrectly attacks healthy tissue. Symptoms may be mild, such as numbness in the
limbs, or severe, such as paralysis or loss of vision. These problems may be permanent
or may come and go. The National MS Society addresses the challenges of each
person affected by MS by funding cutting-edge research, driving change through
advocacy, facilitating professional education, collaborating with MS organizations
around the world, and providing programs and services designed to help people with
MS and their families move their lives forward. For more information about MS, the
Society or to join the MS movement visit: www.nationalMSsociety.org
About Amplimmune, Inc.
Headquartered in Rockville, Maryland, Amplimmune is focused on developing novel
biologics targeting key co-stimulatory/co-inhibitory molecules that rebalance the immune
system and are intended for treating cancer, autoimmune disease, infectious disease,
and transplantation. With its strong development focus, Amplimmune is rapidly
advancing two lead molecules towards clinical development: one in the area of cancer
and the other in the autoimmune disease setting. AMP-224 will be advancing into a
phase 1 clinical trial for cancer in 2010. Working closely with its founders at Johns
Hopkins University and other collaborators, Amplimmune is expanding its technology
base in the area of immune co-stimulatory/co-inhibitory molecules and has assembled a
vast foundation of reagents, models, know-how, and intellectual property to further
develop its product pipeline as well as to discover novel biomarkers, ligands, and
receptors. For more information, please visit the Amplimmune website at: www.amplimmune.com
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